Cambridge faz parceria com AstraZeneca e Medical Research Council em novo laboratório de genômica funcional de classe mundial
A instalação, sediada no Milner Therapeutics Institute, apoiará a descoberta de novos medicamentos e diagnósticos para doenças crónicas através da aplicação de ferramentas biológicas e tecnológicas avançadas, incluindo a edição genética CRISPR.
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)
Cientista olhando para o microscópio - Crédito: Instituto Terapêutico Milner
"Um exemplo fantástico de trabalho conjunto da indústria e da academia para impulsionar a ciência que terá um impacto real na saúde das pessoas no Reino Unido e em todo o mundo."
Andy Neely
A Universidade de Cambridge anunciou hoje uma parceria com a AstraZeneca e o Medical Research Council (MRC) para estabelecer um novo laboratório de genômica funcional de última geração no Milner Therapeutics Institute (MTI). O laboratório passará a fazer parte da Iniciativa de Genômica Funcional Humana do Reino Unido, contribuindo para a ambição do Reino Unido de ter o sistema de saúde genômica mais avançado do mundo.
A genómica funcional investiga os efeitos e impactos das alterações genéticas no nosso ADN e, particularmente, como estas contribuem para as doenças. O CRISPR permite testar alterações específicas do DNA de forma controlada para investigar os efeitos e impactos das alterações genéticas no nosso DNA, revelando seus efeitos nos processos biológicos que causam doenças. Encontrar estes factores de doença é um primeiro passo fundamental no processo de identificação de medicamentos potencialmente transformadores da vida dos pacientes.
A nova instalação, que estará localizada dentro do MTI no Cambridge Biomedical Campus, fornecerá aos pesquisadores de todo o Reino Unido acesso a ferramentas biológicas e tecnológicas em grande escala e abrigará uma avançada plataforma automatizada de triagem CRISPR. Espera-se que, através da utilização de ferramentas, como a edição genética CRISPR, para fornecer informações sobre a relação entre genes e doenças, os cientistas descubram novas oportunidades para desenvolver terapias para doenças crónicas, incluindo doenças cardiovasculares, respiratórias e metabólicas.
O professor Tony Kouzarides, diretor do Milner Therapeutics Institute, disse: “A melhor ciência se baseia na colaboração e estou muito satisfeito que o Milner Therapeutics Institute esteja fazendo parceria com o MRC e a AstraZeneca para lançar este laboratório único de genômica funcional. Isto permitirá a partilha de conhecimentos e recursos para fornecer novos diagnósticos e tratamentos para pessoas com doenças crónicas.”
O Professor Andy Neely, Pró-Vice-Chanceler para Empresas e Relações Comerciais da Universidade de Cambridge, disse: “Esta nova colaboração com a AstraZeneca e a MRC é um exemplo fantástico de indústria e academia trabalhando juntas para impulsionar a ciência que terá um impacto real sobre a saúde das pessoas no Reino Unido e em todo o mundo.”
Dr. Jonathan Pearce, Diretor de Estratégia e Planejamento, MRC, disse: “Estamos trabalhando em Pesquisa e Inovação no Reino Unido para melhorar a saúde, o envelhecimento e o bem-estar. O nosso investimento neste novo laboratório baseia-se na liderança global do Reino Unido em genómica. Nosso apoio permitirá o lançamento do laboratório e fornecerá acesso a pesquisadores de todo o Reino Unido. Através deste investimento, e da Iniciativa mais ampla de Genômica Funcional Humana, iremos melhorar o ecossistema nacional necessário para melhorar a nossa compreensão de como a variação genética impacta a saúde e a doença.”
Sharon Barr, vice-presidente executiva de pesquisa e desenvolvimento de biofarmacêuticos da AstraZeneca, disse: “A colaboração é crucial para alcançar nossa ambição de transformar os cuidados de saúde e fornecer medicamentos que mudam a vida dos pacientes, e parcerias inovadoras como esta nos permitem compartilhar recursos e experiência para avanço da ciência. Este novo laboratório criado como parte da Iniciativa de Genômica Funcional Humana, será líder mundial e desempenhará um papel central na definição do futuro trabalho de genómica funcional em todo o Reino Unido e além.”
O laboratório, que deverá entrar em funcionamento em 2024, proporcionará um centro de excelência e recursos nacionais que combina os pontos fortes e a experiência da academia e da indústria. A sua criação faz parte de uma nova parceria formada entre a MTI, a AstraZeneca e a MRC, e baseia-se na experiência adquirida através de uma colaboração existente entre a MTI, a AstraZeneca e a Cancer Research Horizons, conhecida como AstraZeneca-Cancer Research Horizons Functional Genomics Center (FGC), que tem tem permitido avanços na pesquisa oncológica desde 2018. O FGC está atualmente sediado no MTI e será realocado no próximo ano.
A MTI, a AstraZeneca e a Iniciativa de Genômica Funcional Humana do MRC partilharão instalações, recursos e conhecimentos trabalhando em estreita colaboração para facilitar progressos e inovações mais rápidos.