O estudo examinou as ligaa§aµes entre adversidades na infa¢ncia, relaa§aµes sociais de adultos e concentrazµes de glicocortica³ides
![](data:image/jpeg;base64,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)
O trauma no inicio da vida leva a naveis mais altos de horma´nio do estresse em babuanos. Crédito da imagem: Stacy Rosenbaum
Quando os babuanos sofrem traumas no inicio da vida, apresentam naveis mais altos de horma´nios do estresse na idade adulta - um potencial marcador de problemas de saúde - do que seus pares que não sofrem traumas, mesmo que tenham fortes relações sociais quando adultos, de acordo com um estudo conduzido por um pesquisador da Universidade de Michigan.
O estudo examinou as ligações entre adversidades na infa¢ncia, relações sociais de adultos e concentrações de glicocortica³ides. O objetivo era determinar se uma das razões pelas quais os babuanos que sofrem trauma precoce vivem vidas mais curtas e menos sauda¡veis ​​éporque não conseguem desenvolver fortes relações sociais na idade adulta, o que poderia ser benanãfico para a saúde.
A antropa³loga biológica da UM Stacy Rosenbaum e seus co-autores descobriram que, embora a adversidade no inicio da vida não afetasse fortemente a capacidade dos babuanos de ter relações sociais, qualquer efeito positivo desses relacionamentos era muito menor do que os grandes efeitos negativos dos traumas no inicio da vida.
De fato, os pesquisadores descobriram que, se um babuano experimentou um evento adverso quando bebaª, seus naveis de horma´nio do estresse eram cerca de 9% mais altos que um babuano que não sofreu trauma. Babuanos que experimentaram dois ou mais eventos adversos apresentaram naveis de horma´nio do estresse 14% maiores. Seus resultados são publicados nos Anais da Academia Nacional de Ciências.
Babuanos em um bebedouro."Para muitas pessoas, háconexões muito fortes entre o que acontece em suas primeiras vidas e o que acontece em suas vidas adultas", disse Rosenbaum, professor assistente de antropologia. “Se vocêteve uma infa¢ncia trauma¡tica, éprova¡vel que não seja um adulto muito sauda¡vel. E, se vocêéum adulto que não tem fortes relações sociais, também édesproporcionalmente prova¡vel que não seja sauda¡vel. â€
"Para muitas pessoas, háconexões muito fortes entre o que acontece em suas primeiras vidas e o que acontece em suas vidas adultas"
Stacy Rosenbaum
Rosenbaum disse que existe uma noção popular de que ter fortes relações sociais pode mediar o impacto da adversidade infantil na saúde do adulto.
"Os seres humanos vivem muito tempo, e especialmente com questões de privacidade, érealmente muito difacil estudar esse fena´meno em seres humanos", disse ela. “Mas uma das coisas interessantes sobre isso éque não ocorre apenas em humanos. Ocorre em tudo, de peixes a insetos e anfabios, e certamente em outros primatas. â€
Para testar se os laa§os sociais na idade adulta afetam a relação entre respostas precoces ao trauma e o estresse do adulto, a equipe de pesquisa estudou os naveis de horma´nios glicocortica³ides ou o que as pessoas geralmente chamam de "naveis de horma´nios do estresse" de 192 babuanos selvagens.
Pessoa que coleta dados sobre babuanos.Esses babuanos foram seguidos desde o nascimento pelo Projeto de Pesquisa Amboseli Baboon no Quaªnia. Fundado em 1971 e administrado em conjunto pela Universidade de Notre Dame, Duke University e Princeton University, o projeto de pesquisa fornece dados sobre experiências de vida precoce, vanculos sociais de adultos e naveis de horma´nios glicocortica³ides.
O projeto identificou seis fontes de adversidade precoce para babuanos: nascer durante uma seca; ter um irmão mais novo mais pra³ximo que compete pela atenção e pelos recursos da ma£e; vivendo em um grupo com alta densidade populacional; perder a ma£e em tenra idade; nascer de uma ma£e de baixo escala£o; e nascer de uma ma£e socialmente isolada.
Os pesquisadores usaram concentrações de glicocortica³ides, coletadas das fezes de babuanos ao longo da vida adulta, como uma medida de saúde, porque outras medidas, como medir a temperatura ou coletar sangue, são difaceis para os animais selvagens. Os pesquisadores do projeto também coletam dados sobre as relações sociais dos babuanos: quem éamigo de quem e quanto tempo eles passam se arrumando.
Pesquisas anteriores mostraram que as mulheres que experimentaram três ou mais dessas fontes de adversidade precoce tiveram uma redução de 50% na vida útil em comparação com suas colegas que não experimentaram nenhuma fonte conhecida de adversidade. Mas uma grande pergunta sem resposta foi por quaª? Esses animais poderiam ser mais socialmente isolados, o que poderia contribuir para problemas de saúde e, portanto, uma vida útil mais curta?
“Nãodescobrimos que as relações sociais não afetam a saúde, pelo menos conforme medido pelos glicocortica³ides. a‰ verdade que animais com vanculos sociais mais fortes tem naveis mais baixos de glicocortica³ides, mas apenas um pouco mais baixos â€, disse Rosenbaum. “Mas descobrimos que esses pequenos efeitos positivos foram completamente inundados pelo grande efeito negativo da adversidade no inicio da vida. Em uma nota positiva, os animais que tem coisas ruins ainda parecem ter a capacidade de construir relacionamentos sociais com outros babuanos. â€
O impacto direto da adversidade precoce nas concentrações de glicocortica³ides em adultos foi 11 vezes mais forte que o impacto dos laa§os sociais nos glicocortica³ides. Os animais que sofreram trauma tiveram laa§os sociais um pouco mais fracos do que os animais que não o fizeram, mas sendo apenas um pouco menos sociais, combinados com laa§os sociais com apenas um pequeno efeito nos glicocortica³ides, significavam que as relações sociais não explicavam por que esses animais tem maior estresse concentrações hormonais.
Babuanos com espinhos de aca¡cia.
“Um dos grandes pontos de interrogação aqui éque não queremos misturar horma´nios do estresse e saúde. Os naveis de horma´nio do estresse são apenas uma medida e, especificamente, éuma medida de quanto bem o seu eixo hipota¡lamo-hipa³fise-adrenal estãofuncionando â€, disse Rosenbaum. “Mas sabemos de uma análise separada que esses altos naveis de glicocortica³ides também são bons em prever a morte. Então, acreditamos que isso indica algo importante sobre a saúde de um animal. â€
Um mecanismo possível éque os animais com naveis mais altos de horma´nio do estresse não são tão bons em se recuperar de eventos estressantes. O eixo hipota¡lamo-hipa³fise-adrenal desempenha um papel na regulação da resposta imune, metabolismo, ritmo circadiano e muitos outros processos cruciais para a boa saúde.
"Naveis de estresse constantemente elevados podem ser difaceis para o corpo", disse Rosenbaum. “Em vez de comea§ar com uma colher de prata na boca, esses babuanos estãocomea§ando a partir deste ponto, onde érealmente difacil recuperar o terreno perdido. Fisicamente, seus corpos podem simplesmente ser destruados pelo que estãoacontecendo com eles. Eles nunca conseguem alcana§a¡-lo.
Os coautores de Rosenbaum incluem Shuxi Zeng, Fan Li e Laurence Gesquiere da Duke University; Fernando Campos da Duke e Universidade do Texas em San Antonio; Jeanne Altmann, da Universidade de Princeton; Susan Alberts da Duke e Instituto de Pesquisa de Primatas, Nairobi, Quaªnia; e Elizabeth Archie, da Universidade de Notre Dame e do Instituto de Pesquisa de Primatas.