Os pesquisadores extraaram com sucesso o DNA de uma colea§a£o de blocos de sedimentos preparados há40 anos, em locais na áfrica, asia, Europa e Amanãrica do Norte.
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)
Amostragem de um bloco não perturbado de sedimento impregnado para análises de DNA antigo. Crédito: MPI f. Antropologia Evoluciona¡ria
Os sedimentos nos quais os achados arqueola³gicos estãoembutidos hámuito são considerados pela maioria dos arqueólogos como subprodutos sem importa¢ncia das escavações. No entanto, nos últimos anos, foi demonstrado que os sedimentos podem conter biomoléculas antigas, incluindo DNA. "A recuperação de DNA humano e faunastico antigo de sedimentos oferece novas oportunidades empolgantes para investigar a distribuição geogra¡fica e temporal de humanos antigos e outros organismos em locais onde seus restos esquelanãticos são raros ou ausentes", diz Matthias Meyer, autor saªnior do estudo e pesquisador do Instituto Max Planck de Antropologia Evoluciona¡ria em Leipzig.
Para investigar a origem do DNA no sedimento, os pesquisadores de Max Planck se uniram a um grupo internacional de geoarqueólogos - arqueólogos que aplicam técnicas geola³gicas para reconstruir a formação de sedimentos e satios - para estudar a preservação do DNA em sedimentos em uma escala microsca³pica. Eles usaram blocos intactos de sedimentos que haviam sido previamente removidos de satios arqueola³gicos e embebidos em resina sintanãtica semelhante a um pla¡stico (polianãster). Os blocos endurecidos foram levados ao laboratório e fatiados em seções para imagens microsca³picas e análises genanãticas.
Os pesquisadores extraaram com sucesso o DNA de uma coleção de blocos de sedimentos preparados há40 anos, em locais na áfrica, asia, Europa e Amanãrica do Norte. "O fato de esses blocos serem uma excelente fonte de DNA antigo - incluindo o originado de hominaneos - apesar de muitas vezes serem armazenados em pla¡stico por décadas, fornece acesso a um vasto reposita³rio inexplorado de informações genanãticas. O estudo abre uma nova era de estudos de DNA antigo que revisara¡ as amostras armazenadas em laboratórios, permitindo a análise de locais que foram preenchidos hámuito tempo, o que éespecialmente importante devido a restrição de viagens e a inacessibilidade do local em um mundo pandaªmico ", disse Mike Morley da Flinders University na Austra¡lia, que liderou alguns dos as análises geoarqueola³gicas.
Superfacie de uma seção de bloco não perturbado de sedimento impregnado da
Caverna Denisova. Crédito: Mike Morley
Abunda¢ncia de micro permanece na matriz do sedimento
Os cientistas usaram blocos de sedimentos da caverna Denisova, um local localizado nas montanhas Altai, no centro-sul da Sibanãria, onde DNA antigo de Neandertais, Denisovanos e humanos modernosfoi recuperado e mostrou que pequenaspartículas orga¢nicas renderam mais DNA do que sedimentos amostrados aleatoriamente. "Isso mostra claramente que a alta taxa de sucesso da recuperação de DNA de mamaferos antigos dos sedimentos da Caverna de Denisova vem da abunda¢ncia de micro-restos na matriz do sedimento, e não do DNA extracelular livre de fezes, fluidos corporais ou tecido celular em decomposição potencialmente adsorvido em gra£os minerais, "afirma Vera Aldeias, coautora do estudo e investigadora da Universidade do Algarve, em Portugal. "Este estudo éum grande passo para entender precisamente onde e em que condições o DNA antigo épreservado nos sedimentos", disse Morley.
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A abordagem descrita no estudo permite a amostragem em microescala altamente localizada de sedimentos para análises de DNA e mostra que o DNA antigo (aDNA) não estãouniformemente distribuado no sedimento; e que caracteristicas especaficas dos sedimentos são mais favoráveis ​​a preservação do DNA antigo do que outras. "Ligar o aDNA do sedimento ao micro-contexto arqueola³gico significa que também podemos abordar a possibilidade de movimento fasico do aDNA entre os depa³sitos sedimentares", diz Susan Mentzer, pesquisadora do Centro Senckenberg para Evolução Humana e Paleoambiente (Alemanha).
Diyendo Massilani, o principal autor do estudo, foi capaz de recuperar quantidades substanciais de DNA de Neandertal de apenas alguns miligramas de sedimento. Ele pa´de identificar o sexo dos indivíduos que deixaram seu DNA para trás e mostrou que eles pertenciam a uma população aparentada com um Neandertal cujo genoma foi previamente reconstruado a partir de um fragmento de osso descoberto na caverna. “O DNA do Neandertal nessas pequenas amostras de sedimento embutido em pla¡stico era muito mais concentrado do que o que normalmente encontramos em material soltoâ€, diz ele. "Com esta abordagem, serápossível, no futuro, analisar o DNA de muitos indivíduos humanos antigos a partir de apenas um pequeno cubo de sedimento solidificado. a‰ divertido pensar que presumivelmente seja assim porque eles usaram a caverna como banheiro hádezenas de milhares de anos. "
A pesquisa foi publicada em Proceedings of the National Academy of Sciences .