Os documentos mais recentes adicionados ao Opioid Industry Documents Archive ilustram a repetida falha das farmácias de varejo em atender aos sinais de alerta e às diretrizes de segurança
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A Universidade Johns Hopkins e a Universidade da Califórnia, San Francisco, ou UCSF, adicionaram novos documentos ao Arquivo de Documentos da Indústria de Opióides que detalham o papel das farmácias de varejo na epidemia de overdose de opióides.
Os documentos, baseados em litígios liderados pelo procurador-geral da Flórida, os condados de Lake e Trumbull de Ohio e o procurador da cidade de São Francisco, mostram como empresas como CVS, Rite-Aid, Target, Walgreens e Walmart falharam repetidamente em empregar salvaguardas para evitar a dispensa excessiva e o desvio de substâncias controladas potencialmente perigosas.
Os registros do tribunal mostram que as farmácias ignoraram repetidamente as políticas e diretrizes rígidas da Drug Enforcement Administration, ou DEA, projetadas para proteger pacientes que recebem substâncias controladas como opióides prescritos. Os registros também mostram que muitas dessas farmácias enfrentaram repetidamente ações disciplinares por não tomarem medidas corretivas após violarem as regras. Exemplos incluem:
Não seguir as diretrizes da DEA sobre dispensação de medicamentos
Deixar de relatar vendas suspeitas de drogas à DEA
Não ter (ou não seguir) um plano para prevenir o desvio ilegal de drogas
No caso da Walgreens, envolver-se em marketing enganoso ao não informar os pacientes sobre os perigos dos opióides
O arquivo, lançado pelas duas universidades de pesquisa em março de 2021 , é um repositório digital de documentos divulgados publicamente decorrentes de litígios movidos contra fabricantes de opioides e consultores de fabricantes, distribuidores e farmácias por governos locais e estaduais e comunidades tribais. Durante décadas, à medida que o vício em opiáceos e as mortes aumentavam, o público sabia muito pouco sobre o negócio oculto de fabricar e vender analgésicos prescritos. Milhares de ações judiciais desde então lançaram luz sobre as práticas do setor. O arquivo está coletando o maior número possível de documentos e compartilhando-os livremente.
"Muita atenção tem sido dada ao papel de fabricantes farmacêuticos como Purdue em causar a epidemia de opióides. Mas os documentos do arquivo estão mostrando ao público com grande detalhe que os fabricantes de medicamentos não criaram esta tragédia por si mesmos", disse G. Caleb Alexander , professor de epidemiologia e medicina na Johns Hopkins Bloomberg School of Public Health e diretor co-fundador de seu Centro de Segurança e Eficácia de Medicamentos . Alexander, que atuou como especialista remunerado em litígios federais e estaduais de opióides, acrescentou: "Há um longo caminho desde o fabricante de pílulas até o público, com vários atores, incluindo farmácias no meio".
A adição de mais de 2.200 documentos farmacêuticos expandirá a coleção do arquivo de mais de 1,5 milhão de documentos da indústria de opióides. O arquivo pode ser útil para muitas partes diferentes, incluindo famílias prejudicadas pela crise dos opiáceos, bem como a mídia, profissionais de saúde, estudantes, advogados e pesquisadores.
"OS DOCUMENTOS DO ARQUIVO ESTaO MOSTRANDO AO PÚBLICO COM GRANDE DETALHE QUE OS FABRICANTES DE MEDICAMENTOS NaO CRIARAM ESTA TRAGÉDIA POR SI MESMOS."
G. Caleb Alexandre
Professor de epidemiologia e medicina
Os documentos são pesquisáveis ??em texto completo e incluem uma variedade de materiais relevantes, incluindo e-mails da empresa, memorandos, apresentações, relatórios de vendas, orçamentos, relatórios de auditoria, briefings da Drug Enforcement Administration, agendas e atas de reuniões, relatórios de testemunhas especializadas e transcrições de julgamentos.
O arquivo de opióides é inspirado no pioneiro arquivo Truth Tobacco Industry Documents da UCSF , que promoveu descobertas científicas e de saúde pública que moldaram a política do tabaco nos EUA e em todo o mundo. Como sua contraparte, o arquivo de opioides foi projetado para acomodar novos documentos de futuros acordos ou julgamentos à medida que o litígio continua.
Ele permitirá que pesquisadores e historiadores encontrem e analisem padrões e práticas negativas de comportamento da indústria que podem levar a novas políticas e leis para proteger o público de comportamentos criminosos, antiéticos e perigosos.
De acordo com os Centros de Controle e Prevenção de Doenças, a primeira onda de mortes por overdose de opioides nos EUA começou em 1999 com o aumento da prescrição de opioides na década de 1990. Entre 1999 e 2020, de acordo com o CDC, mais de 564.000 pessoas nos EUA tiveram uma overdose fatal de opioides prescritos e ilícitos. A análise mais recente do Conselho de Assessores Econômicos da Casa Branca estima que a epidemia de opioides custou US$ 696 bilhões em 2018 e mais de US$ 2,5 trilhões entre 2015 e 2018.
"Esses documentos são de grande importância, agora e a longo prazo", disse Kate Tasker, arquivista-gerente da Biblioteca de Documentos da Indústria da UCSF. "Estamos disponibilizando-os ao público o mais rápido possível para que possam informar as atuais investigações e ações de saúde pública, mas também estamos trabalhando para preservá-los para futuras gerações de pesquisadores, historiadores, formuladores de políticas e outros que desejam evitar danos como que isso aconteça novamente."