Pesquisadores encontram resposta imune mais forte contra o vírus herpes simplex 2 em camundongos obesos
Uma equipe de pesquisadores do Instituto Avançado de Ciência e Tecnologia da Coreia, trabalhando com um colega do Myunggok Medical Research Center, descobriu que ratos de teste intencionalmente superalimentados para torná-los obesos...
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)
Domínio público
Uma equipe de pesquisadores do Instituto Avançado de Ciência e Tecnologia da Coreia, trabalhando com um colega do Myunggok Medical Research Center, descobriu que ratos de teste intencionalmente superalimentados para torná-los obesos apresentam uma resposta imune mais forte contra o vírus herpes simplex 2 do que os ratos alimentados normalmente. Em seu artigo publicado na revista Cell Reports , o grupo descreve seu trabalho com testes de resposta imune em camundongos de laboratório e o que eles encontraram.
Pesquisas anteriores mostraram que a obesidade em humanos pode levar a doenças cardiovasculares e, em alguns casos, a um risco maior de desenvolver alguns tipos de câncer. Estudos também encontraram evidências de que, em alguns casos, a obesidade pode levar a um sistema imunológico comprometido. Por outro lado, a obesidade nunca foi associada a um risco aumentado de desenvolver ou morrer de câncer do colo do útero, que foi causado principalmente por infecções pelo papilomavírus humano (HPV).
Pesquisas anteriores também mostraram que, se camundongos de laboratório forem infectados com o vírus herpes simplex 2, eles são superados rapidamente e morrem em questão de semanas. Nesse novo esforço, os pesquisadores se perguntaram se camundongos de laboratório obesos morreriam mais rápido de tal infecção, talvez devido a um sistema imunológico enfraquecido. Para descobrir, eles alimentaram um grupo de ratos de laboratório com uma dieta rica em gordura e outro com uma dieta magra. Eles mantiveram isso até que os ratos da dieta rica em gordura se tornassem obesos. Em seguida, eles coletaram intravaginalmente todos os camundongos de teste com o vírus herpes simplex 2.
Ao monitorar os camundongos, os pesquisadores descobriram, para sua surpresa, que metade dos camundongos obesos sobreviveu à infecção, enquanto todos os camundongos magros morreram. Eles também descobriram que os níveis do vírus nos camundongos obesos começaram a desaparecer mais rapidamente do que nos camundongos magros.
Olhando mais de perto, os pesquisadores encontraram níveis mais altos de células T citotóxicas gama-delta (??) na mucosa vaginal das camundongos fêmeas. Quando eles inibiram essas células, os camundongos perderam a capacidade de combater o vírus, mostrando que eram as células T ?? que estavam dando aos camundongos a capacidade de combater o vírus. Eles também descobriram que a injeção intravaginal de antibióticos nos ratos reduzia sua capacidade de combater o vírus.