Sonhos ruins em crianças estão ligados a um maior risco de demência e doença de Parkinson na idade adulta, revela novo estudo
Os sonhos das crianças podem prever eventos que acontecerão quase 40 anos no futuro? Sim, de acordo com os resultados do meu último estudo publicado na revista eClinicalMedicine .
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)
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Os sonhos das crianças podem prever eventos que acontecerão quase 40 anos no futuro? Sim, de acordo com os resultados do meu último estudo publicado na revista eClinicalMedicine .
Mais especificamente, mostrou que crianças que têm sonhos ruins e pesadelos regulares entre as idades de sete e 11 anos podem ter quase duas vezes mais chances de desenvolver comprometimento cognitivo (a principal característica da demência ) quando atingem os 50 anos. ser até sete vezes mais propensos a serem diagnosticados com a doença de Parkinson aos 50 anos.
Para obter informações sobre essas descobertas surpreendentes, em 2022 descobri que adultos de meia-idade e mais velhos que têm pesadelos e pesadelos frequentes podem ter duas vezes mais chances de desenvolver demência ou Parkinson no futuro.
Dado que uma grande proporção de pessoas que experimentam pesadelos regulares quando adultos também relatam ter tido pesadelos regulares quando eram crianças , isso me fez pensar se ter muitos pesadelos durante a infância pode prever o desenvolvimento de demência ou doença de Parkinson mais tarde na vida.
Para descobrir, usei dados do conhecido estudo britânico de coorte de nascimentos de 1958 , que acompanha a vida de todas as crianças nascidas na Inglaterra, Escócia e País de Gales durante a semana de 3 a 9 de março de 1958.
Quando as crianças tinham sete anos (1965) e 11 anos (1969), suas mães responderam a uma série de perguntas sobre sua saúde, inclusive se haviam tido pesadelos nos últimos três meses (sim/não).
Agrupei as 6.991 crianças com base na regularidade com que tiveram pesadelos aos 7 e 11 anos: "nunca", "ocasional" ou "persistente". Em seguida, usei um software estatístico para determinar se as crianças com pesadelos mais regulares eram mais propensas a desenvolver comprometimento cognitivo ou serem diagnosticadas com Parkinson quando completassem 50 anos (2008).
Os resultados foram claros. Quanto mais regularmente as crianças tivessem pesadelos, maior a probabilidade de desenvolverem comprometimento cognitivo ou serem diagnosticados com a doença de Parkinson.
Notavelmente, em comparação com crianças que nunca tiveram pesadelos, aquelas que tiveram pesadelos persistentes tiveram 76% mais chances de desenvolver comprometimento cognitivo e 640% mais chances de desenvolver Parkinson. Esse padrão foi semelhante para meninos e meninas.
Esses resultados sugerem que ter sonhos ruins e pesadelos regulares durante a infância pode aumentar o risco de desenvolver doenças cerebrais progressivas, como demência ou doença de Parkinson, mais tarde na vida. Eles também levantam a possibilidade intrigante de que reduzir a frequência dos sonhos ruins durante o início da vida pode ser uma oportunidade precoce para prevenir ambas as condições.
Mais estudos serão necessários para confirmar se pesadelos e pesadelos realmente causam essas condições.
A frequência com que temos pesadelos quando crianças é determinada em grande parte por nossa genética . E um gene conhecido por aumentar nosso risco de ter pesadelos regulares ( PTPRJ ) também está ligado ao aumento do risco de desenvolver a doença de Alzheimer na velhice. Portanto, é possível que pesadelos e doenças cerebrais progressivas sejam causadas por um conjunto compartilhado de genes.
Meu palpite é que ambas as teorias podem ser verdadeiras. Ou seja, pesadelos e doenças cerebrais progressivas estão ligados por genética compartilhada, bem como através de pesadelos que causam diretamente doenças cerebrais ao interromper os elementos do sono que restauram o cérebro .
Não se assuste
Embora essas descobertas pareçam alarmantes, colocadas em seu devido contexto, elas não deveriam ser. Das cerca de 7.000 crianças incluídas em meu estudo, apenas 268 (4%) tiveram pesadelos persistentes de acordo com suas mães. Entre essas crianças, apenas 17 desenvolveram comprometimento cognitivo ou doença de Parkinson aos 50 anos (6%).
Portanto, é provável que a grande maioria das pessoas que têm pesadelos persistentes na infância não desenvolva demência precoce ou Parkinson.
No entanto, o risco de desenvolver doenças cerebrais progressivas aumenta substancialmente na velhice. Estar ciente de que pesadelos na infância podem sinalizar um risco maior de demência ou Parkinson mais tarde na vida sugere que pode haver uma janela de oportunidade para implementar estratégias simples para reduzir esses riscos. E para os jovens com sonhos angustiantes frequentes que persistem ao longo do tempo, obter ajuda para pesadelos pode ser uma dessas estratégias.
O próximo passo da minha pesquisa é usar a eletroencefalografia (uma técnica para medir as ondas cerebrais) para examinar as razões biológicas dos pesadelos e pesadelos em crianças.
A longo prazo, o objetivo será usar esse conhecimento para desenvolver novos tratamentos para todas as pessoas atormentadas por pesadelos e pesadelos. O objetivo final é melhorar a qualidade do sono e a saúde mental e reduzir a chance de desenvolver demência ou doença de Parkinson mais tarde na vida.
Mais informações: Abidemi I. Otaiku, Sonhos angustiantes na infância e risco de comprometimento cognitivo ou doença de Parkinson na idade adulta: um estudo nacional de coorte de nascimentos, eClinicalMedicine (2023). DOI: 10.1016/j.eclinm.2023.101872
Informações da revista: EClinicalMedicine