Adicionar medicamento antipsicótico ao antidepressivo pode ajudar idosos com depressão resistente ao tratamento
Para adultos mais velhos com depressão clínica que não responderam aos tratamentos padrão, adicionar o medicamento aripiprazol (nome comercial Abilify) a um antidepressivo que eles já estão tomando é mais eficaz do que mudar de um...
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)
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Para adultos mais velhos com depressão clínica que não responderam aos tratamentos padrão, adicionar o medicamento aripiprazol (nome comercial Abilify) a um antidepressivo que eles já estão tomando é mais eficaz do que mudar de um antidepressivo para outro, de acordo com um novo estudo multicêntrico liderado por Escola de Medicina da Universidade de Washington em St. Louis.
O aripiprazol foi originalmente aprovado pelo FDA em 2002 como tratamento para esquizofrenia, mas também tem sido usado em doses mais baixas como tratamento adicional para depressão clínica em pacientes mais jovens que não respondem apenas aos antidepressivos.
As novas descobertas foram publicadas em 3 de março no The New England Journal of Medicine e serão apresentadas no mesmo dia por Eric J. Lenze, MD - investigador principal e chefe do Departamento de Psiquiatria da Universidade de Washington - e colegas na reunião anual da da Associação Americana de Psiquiatria Geriátrica em Nova Orleans.
Muitas pessoas com depressão clínica não respondem aos medicamentos usados ??para tratar a doença. Consequentemente, alguns médicos mudam esses pacientes para diferentes antidepressivos na busca de encontrar um que funcione, enquanto outros médicos podem prescrever outra classe de medicamentos para ver se uma combinação de medicamentos ajuda.
Ambas as estratégias foram recomendadas por especialistas como opções para idosos com depressão resistente ao tratamento . No entanto, o novo estudo foi projetado para ajudar a determinar qual estratégia é mais eficaz. O aumento de um antidepressivo com aripiprazol ajudou 30% dos pacientes com depressão resistente ao tratamento, em comparação com apenas 20% que mudaram para outro antidepressivo individual, mostram os resultados do estudo.
“Muitas vezes, a menos que um paciente responda ao primeiro tratamento prescrito para a depressão, os médicos seguem um padrão no qual tentam um tratamento após o outro até chegarem a um medicamento eficaz”, disse Lenze, professor de Wallace e Lucille Renard e autor correspondente do estudo. .
"Seria benéfico ter uma estratégia baseada em evidências na qual podemos confiar para ajudar os pacientes a se sentirem melhor o mais rápido possível. Descobrimos que a adição de aripiprazol levou a taxas mais altas de remissão da depressão e maiores melhorias no bem-estar psicológico - o que significa como pacientes positivos e satisfeitos sentiram - e isso é uma boa notícia. No entanto, mesmo essa abordagem ajudou apenas cerca de 30% das pessoas no estudo com depressão resistente ao tratamento, ressaltando a necessidade de encontrar e desenvolver tratamentos mais eficazes que possam ajudar mais pessoas.
A depressão resistente ao tratamento não é mais ou menos comum em pessoas mais velhas do que em pessoas mais jovens, mas como parece acelerar o declínio cognitivo , é muito importante identificar maneiras mais eficazes de tratá-la.
Lenze, juntamente com colegas da Columbia University, UCLA, University of Pittsburgh e University of Toronto, estudaram 742 pessoas, com 60 anos ou mais, com depressão resistente ao tratamento, o que significa que a depressão não respondeu a pelo menos dois medicamentos antidepressivos diferentes.
Os pesquisadores avaliaram as estratégias comumente usadas na prática clínica para ajudar a aliviar a depressão resistente ao tratamento em pacientes idosos e projetaram o estudo para ter duas fases distintas. Na primeira fase, 619 pacientes, cada um tomando um antidepressivo como Prozac, Lexapro ou Zoloft, foram divididos aleatoriamente em três grupos. No primeiro grupo, os pacientes permaneceram em qualquer medicamento antidepressivo que já estivessem tomando, mas também receberam o medicamento aripiprazol (Abilify).
Um segundo grupo também continuou tomando antidepressivos, mas acrescentou bupropiona (marcas Wellbutrin ou Zyban), e um terceiro grupo diminuiu gradualmente o antidepressivo que cada um estava tomando e mudou totalmente para bupropiona.
Ao longo de 10 semanas, os participantes receberam telefonemas quinzenais ou visitas pessoais com os médicos do estudo. Nessas visitas, os medicamentos foram ajustados de acordo com a resposta individual do paciente e os efeitos colaterais. Os pesquisadores descobriram que o grupo que apresentou os melhores resultados gerais foi aquele em que os pacientes continuaram com seus antidepressivos originais, mas acrescentaram aripiprazol.
Os pesquisadores também previram que algumas pessoas no estudo não responderiam aos vários tratamentos, então adicionaram uma segunda fase que incluiu 248 participantes. Nessa fase, os pacientes que tomavam antidepressivos como Prozac, Lexapro e Zoloft eram tratados com lítio ou nortriptilina – medicamentos amplamente usados ??antes que outros antidepressivos mais novos fossem aprovados há mais de duas décadas. As taxas de alívio da depressão na segunda fase do estudo foram baixas, cerca de 15%. E não houve um vencedor claro quando o aumento com lítio foi comparado com a mudança para nortriptilina.
"Essas drogas mais antigas também são um pouco mais complicadas de usar do que os tratamentos mais novos", explicou Lenze. "O lítio, por exemplo, requer exames de sangue para garantir sua segurança, e é recomendado que os pacientes que tomam nortriptilina façam eletrocardiogramas periodicamente para monitorar a atividade elétrica do coração. Como nem o lítio nem a nortriptilina foram promissores contra a depressão resistente ao tratamento em adultos mais velhos, esses medicamentos são improvável que seja útil na maioria dos casos."
Mas mesmo a melhor estratégia de tratamento – adicionar aripiprazol a um antidepressivo – não foi muito bem-sucedida para muitos pacientes idosos com depressão resistente ao tratamento.
"Isso realmente destaca um problema contínuo em nosso campo", disse o autor sênior Jordan F. Karp, MD, professor e presidente do Departamento de Psiquiatria da Faculdade de Medicina da Universidade do Arizona - Tuscon. "É provável que qualquer tratamento ajude apenas um subconjunto de pessoas e, idealmente, gostaríamos de saber, com antecedência, quem tem maior probabilidade de ser ajudado, mas ainda não sabemos como determinar isso."
Lenze enfatizou que, em geral, os antidepressivos são altamente úteis para a maioria das pessoas que sofrem de depressão clínica. Pelo menos metade de todas as pessoas com depressão se sente muito melhor depois de começar a tomar o primeiro medicamento que experimenta. E quase metade do restante não ajudado por uma primeira droga melhora quando muda para uma segunda droga, mas isso deixa um grupo considerável com depressão clínica que não responde a dois tratamentos.
O problema é particularmente difícil em adultos mais velhos, muitos dos quais já estão tomando vários medicamentos para outras condições, como pressão alta, problemas cardíacos ou diabetes", disse Lenze. "Portanto, mudar para novos antidepressivos a cada poucas semanas ou adicionar outras drogas psiquiátricas pode ser complicado. Além disso, como a depressão e a ansiedade em idosos podem acelerar o declínio cognitivo, é urgente encontrar estratégias de tratamento mais eficazes.
“Definitivamente há algo que torna a depressão mais difícil de tratar nessa população, uma população que só vai crescer à medida que nossa sociedade envelhece”, acrescentou.
Mais informações: Eric J. Lenze et al, Antidepressant Augmentation versus Switch in Treatment-Resistant Geriatric Depression, The New England Journal of Medicine (2023). DOI: 10.1056/NEJMoa2204462 . www.nejm.org/doi/full/10.1056/NEJMoa2204462
Informações do periódico: New England Journal of Medicine