Novos insights sobre como os músculos mudam durante o treinamento de resistência
Quanto mais exercitamos a nossa resistência, mais em forma nos tornamos – e os nossos músculos também. Eles se adaptam à carga e conseguem ter um desempenho melhor por um longo período de tempo. Uma equipe de pesquisa da Universidade de Basileia...
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)
Os músculos adaptam-se ao treino de resistência, tornando-se assim mais eficientes e resistentes. Crédito: Pixabay
Quanto mais exercitamos a nossa resistência, mais em forma nos tornamos – e os nossos músculos também. Eles se adaptam à carga e conseguem ter um desempenho melhor por um longo período de tempo. Uma equipe de pesquisa da Universidade de Basileia descobriu agora novos insights sobre essas adaptações musculares por meio de experimentos realizados em ratos.
O treinamento de resistência é benéfico. Os treinos regulares não só melhoram a aptidão física e o bem-estar, mas também desencadeiam uma profunda remodelação muscular. Isto reflete-se nos efeitos típicos do treino: os músculos fadigam-se menos rapidamente, fornecem mais energia e utilizam o oxigénio de forma mais eficiente.
“A adaptação dos músculos à atividade física é um fenômeno bem conhecido”, diz o Prof. Christoph Handschin, que há muito pesquisa biologia muscular no Biozentrum da Universidade de Basileia. “Queríamos entender o que exatamente acontece no músculo durante o treinamento físico ”. Ele e sua equipe publicaram agora novos insights na Nature Metabolism .
O estado de treinamento é refletido nos genes
No presente estudo, a equipe de Handschin comparou músculos de ratos não treinados com os de ratos treinados e investigou como a expressão genética muda em resposta aos exercícios. “Como o treinamento de resistência induz uma remodelação muscular substancial, presumimos que as adaptações se refletiriam na expressão genética ”, diz a primeira autora, Regula Furrer.
"No entanto, em contraste com nossas expectativas, a expressão de relativamente poucos, cerca de 250 genes , foi alterada em músculos treinados em repouso em comparação com músculos não treinados em repouso. Surpreendentemente, cerca de 1.800 a 2.500 genes foram regulados após uma sessão aguda de exercício. Quantos e quais a resposta dos genes depende em grande parte do estado de treinamento."
Os músculos respondem de maneira diferente ao estresse físico
Em músculos não treinados, por exemplo, o treino de resistência ativa genes inflamatórios, desencadeados por pequenas lesões que causam o que conhecemos como dor muscular.
"Não pudemos observar isso em ratos treinados; em vez disso, os genes que protegem o músculo são mais ativos. Assim, os músculos treinados respondem de forma completamente diferente ao estresse do exercício", explica Furrer. “Eles são mais eficientes e resilientes – em suma, conseguem lidar melhor com a carga física.”
Padrão epigenético molda a aptidão muscular
A questão é: como é possível que os músculos respondam de forma tão diferente ao exercício de resistência dependendo do seu estado de treino? Os cientistas encontraram uma resposta na epigenética.
Os genes são ativados ou desativados pelas chamadas modificações epigenéticas, marcas químicas no genoma. “Foi surpreendente que o padrão epigenético entre músculos não treinados e treinados seja totalmente diferente e que muitas dessas modificações ocorram em genes-chave que controlam a expressão de vários outros genes”, enfatiza Furrer. Consequentemente, o exercício ativa um programa completamente diferente nos músculos treinados em comparação aos não treinados.
Esta informação epigenética determina como o músculo responde ao treinamento. "O treino de resistência crónico altera o padrão epigenético do músculo, tanto a curto como a longo prazo. Parece que os músculos treinados estão preparados para treinos prolongados devido ao seu padrão epigenético. Eles respondem muito mais rapidamente e trabalham com mais eficiência", resume Handschin. “A cada sessão de treino , a resistência muscular aumenta.”
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)
Um baixo número de genes diferencialmente expressos (DEGs) define um músculo WT
treinado. a , Todos os clusters de anotação funcional de proteínas reguladas para cima
(laranja) e reguladas negativamente (azul) em músculos treinados com uma pontuação de
enriquecimento> 2. ROS, espécies reativas de oxigênio. b , Exemplos de proteínas envolvidas
na resposta ao estresse em músculos sedentários não treinados (cinza claro) e não
perturbados (cinza escuro) (os box plots exibem a mediana e os percentis 25 a 75 e os
bigodes indicam os valores mínimo e máximo). c , Número de genes expressos
diferencialmente em músculos treinados não perturbados (ponto de corte: FDR < 0,05; log 2
(FC) ± 0,6). d, Todos os agrupamentos de anotação funcional de genes regulados para cima
(laranja) e negativamente (azul) em músculos treinados com uma pontuação de
enriquecimento> 2. e , Motivos de fatores de transcrição da ISMARA que estão entre aqueles
com maior e menor atividade. UA, unidades arbitrárias. f , Número de genes após um
período agudo de exercício de exaustão que são regulados para cima (laranja) e para baixo
(azul). g , Diagrama de Venn de todos os genes que são alterados no músculo treinado não
perturbado (o laranja é regulado positivamente e o azul é regulado negativamente) e
aqueles que são regulados após uma sessão aguda de exercício máximo (cor clara, linha
tracejada). h, Mapa de calor de todos os genes expressos diferencialmente em músculos
treinados imperturbados para visualizar a sobreposição com genes regulados de forma
aguda usando agrupamento hierárquico de distância euclidiana para linhas. Os dados são de
cinco réplicas biológicas e representam média ± sem (salvo indicação em contrário). As
estatísticas dos dados proteômicos foram realizadas usando estatísticas t empíricas
moderadas por Bayes, conforme implementadas no pacote R / Bioconductor limma e para
dados de RNA-seq com o software CLC Genomics Workbench. Os valores P exatos dos dados
proteômicos e os escores z dos dados ISMARA são exibidos em Dados de origem. O asterisco
indica diferença para o controle (Ctrl; condição pré-exercício) se não for indicado de outra
forma: in b , * P<0,05, em e , * pontuação z > 1,96 (Dados Estendidos Fig. 1 e Tabelas
Suplementares 1–4). Crédito: Nature Metabolism (2023). DOI: 10.1038/s42255-023-00891-y
Do rato ao humano
Os pesquisadores revelaram como os músculos se adaptam ao treinamento regular de resistência ao longo do tempo em ratos. O próximo passo é descobrir se esses resultados também podem ser transferidos para humanos. Nos desportos competitivos , biomarcadores que reflectem o progresso do treino podem ser utilizados para melhorar a eficiência do treino.
Mais importante ainda, “compreender como funciona um músculo saudável permite-nos compreender o que corre mal nas doenças”, diz Handschin. Isto é crucial para desbloquear caminhos inovadores para o tratamento da perda muscular relacionada com a idade ou doenças.
Mais informações: Regula Furrer et al, Controle molecular da adaptação ao treinamento de resistência no músculo esquelético de camundongos machos, Nature Metabolism (2023). DOI: 10.1038/s42255-023-00891-y
Informações da revista: Nature Metabolism