Experimentos realizados em modelos animais mostram que uma mutaa§a£o na proteana sãodio-pota¡ssio ATPase resulta na redua§a£o de neuroinflamaa§aµes
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)
Fotomontagem de Moisanãs Dorado/Jornal da USP sobre imagens Fapesp, NIH Image Gallery/Flickr-CC e Wikimedia Commons
Pesquisadores da USP e da Universidade de Aarhus, na Dinamarca, identificaram que uma mutação da proteana sãodio-pota¡ssio ATPase (Na+/K+-ATPase) tem capacidade de reduzir a neuroinflamação em experimentos animais. A descoberta abre caminhos para uma melhor compreensão sobre doenças neurodegenerativas e neuropsiquia¡tricas como Parkinson, Alzheimer, Esclerose Lateral, depressão e ansiedade e, no futuro, possivelmente, o desenvolvimento de novos tratamentos.
A proteana sãodio-pota¡ssio ATPase éresponsável pelo equilabrio ia´nico de todas as células humanas e animais. Ou seja, ela transporta aons de pota¡ssio e de sãodio para o interior e exterior das células, respectivamente, para que estas funcionem saudavelmente.Â
“A proteana sãodio-pota¡ssio ATPase mantanãm os gradientes eletroquímicos das células, mantanãm o equilabrio das concentrações de aons entre a parte interna e externa da membrana celularâ€, diz a autora da pesquisa, Jacqueline Alves Leite, ao Jornal da USP.
A pesquisa de doutorado foi realizada sob orientação do professor Cristoforo Scavone, do Laborata³rio de Neurofarmacologia Molecular do Instituto de Ciências Biomédicas (ICB) da USP, e foi desenvolvida em parceria com pesquisadores da Universidade de Aarhus, na Dinamarca, entre eles, Karin Lykke-Hartmann, a co-orientadora do trabalho.
Os resultados da pesquisa foram publicados na revista Scientific Reports. O trabalho contou com apoio da Fundação de Amparo a Pesquisa do Estado de Sa£o Paulo (Fapesp).
Subunidades da proteana sãodio-pota¡ssio ATPase
Segundo a pesquisadora, a proteana sãodio-pota¡ssio ATPase estãosubdividida em unidades alfa, beta e gama, cada uma delas cumprindo suas respectivas funcionalidades no organismo. As subunidades alfas, por sua vez, se apresentam em isoformas alfa-1, alfa-2, alfa-3 e alfa-4 e agem também de forma diferente em cada tecido a que elas pertencem. A isoforma alfa-1 atua em todas as células; a alfa-2 , nas células neuronais (astra³citos), cardaacas, adiposas e musculares; a alfa-3, nos neura´nios, e a alfa-4, nos espermatozoides.
O trabalho de Jacqueline analisou como as células gliais de camundongos geneticamente modificados na subunidade alfa-2 da proteana sãodio-pota¡ssio ATP base reagiriam a processos inflamata³rios induzidos por endotoxinas lipopolissacaradeos (LPS) de bactanãrias Gram negativas. O LPS promove um estamulo de células do Sistema Nervoso Central (SNC) desencadeando uma resposta neuroinflamata³ria.
“A alfa-2 tem a capacidade de retirar o glutamato, que éo principal neurotransmissor excitata³rio do SNC, da fenda sina¡ptica dos neura´nios e que, em excesso, se torna ta³xico, provocando neuroinflamação. Falhas nesse mecanismo levam a degeneração dos neura´nios, que resulta em doenças neurodegenerativasâ€, explica Jacqueline, atualmente professora do Instituto de Ciências Biola³gicas da Universidade Federal de Goia¡s.
A professora Karin forneceu os animais com a mutação na subunidade “alfa-2â€criados por sua equipe, em laboratório, que também pesquisa terapias gaªnicas para melhorar o quadro de pacientes com doenças que acometem o SNC.
Animais mutados na subunidade alfa-2 da ATPase
A pesquisa consistiu em analisar como as células neuronais de camundongos
geneticamente modificados na subunidade alfa2, da ATpase, reagiriam
a processos inflamata³rios osArte: Jornal da USP
Jacqueline explica que trabalhos anteriores realizados pela equipe do professor Scavone já haviam demonstrado que a supressão da subunidade alfa-2 inibia processos neuroinflamata³rios em células isoladas do Sistema Nervoso Central (SNC). Os experimentos realizados em animais na Universidade de Aarhus, na Dinamarca, consistiram em administrar endotoxinas LPS em ratos com e sem mutação na subunidade alfa-2 da proteana sãodio-pota¡ssio ATPase.
Apa³s esse procedimento, quatro horas depois, os camundongos geneticamente modificados, que tinham a deficiência de alfa-2, apresentaram redução do processo neuroinflamata³rio, devido a uma menor sinalização de LPS.Â
“Foi observado uma redução de citocinas inflamata³rias tanto no sistema nervoso central quanto no sangue dos animais mutadosâ€, diz. Já os animais selvagens, que estavam com os naveis de alfa2 intactos, apresentaram comportamento doentio, ou seja, eles tiveram maior perda de memória, hipotermia e menor locomoção.
Para o futuro, o grupo do professor Scavone pretende continuar os trabalhos para avaliar os efeitos da deficiência da alfa-2 em modelos animais com inflamações crônicas, o que levaria a morte neuronal e consequentemente a s doenças neurodegenerativas. Os experimentos atuais verificaram o potencial dessa proteana em inflamações agudas, em curto prazo.