Estudo identificamudanças genanãticas que provavelmente permitiram que o SARS-CoV-2 passasse dos morcegos para os humanos
As adaptaa§aµes genanãticas identificadas foram semelhantes a s feitas pelo SARS-CoV - que causou a epidemia de SARS de 2002-2003 - quando se adaptou de morcegos para infectar humanos.
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)
Morcegos-ferradura - Crédito: orientando no Flickr
Um novo estudo, envolvendo a Universidade de Cambridge e liderado pelo Instituto Pirbright, identificoumudanças genanãticas importantes no SARS-CoV-2 - o varus que causa o COVID-19 - que pode ser responsável pelo salto dos morcegos para os humanos, e estabeleceu quais animais tem receptores celulares que permitem que o varus entre em suas células de forma mais eficaz.
a‰ essencial entender quais animais podem ser infectados pelo SARS-CoV-2 e como as mutações na proteana do pico viral alteram sua capacidade de infectar diferentes espanãcies
Stephen Graham
As adaptações genanãticas identificadas foram semelhantes a s feitas pelo SARS-CoV - que causou a epidemia de SARS de 2002-2003 - quando se adaptou de morcegos para infectar humanos. Isso sugere que pode haver um mecanismo comum pelo qual essa familia de varus sofre mutação para passar de animais para humanos. Esse entendimento pode ser usado em pesquisas futuras para identificar varus circulando em animais que poderiam se adaptar para infectar humanos (conhecidos como zoonoses) e que potencialmente representam uma ameaça de pandemia.
“Este estudo usou uma plataforma não infecciosa e segura para sondar como as alterações da proteana de pico afetam a entrada do varus nas células de diferentes animais selvagens, de gado e de companhia, algo que precisaremos continuar monitorando de perto a medida que outras variantes do SARS-CoV-2 surgem em nos pra³ximos meses â€, disse o Dr. Stephen Graham, do Departamento de Patologia da Universidade de Cambridge, que esteve envolvido no estudo.
Na epidemia de SARS de 2002-2003, os cientistas foram capazes de identificar isolados intimamente relacionados em morcegos e civetas - nos quais se acredita que o varus se adaptou para infectar humanos. No entanto, no atual surto de COVID-19, os cientistas ainda não sabem a identidade do hospedeiro intermediário ou tem amostras semelhantes para analisar. Mas eles tem a sequaªncia de um coronavarus de morcego relacionado, chamado RaTG13, que compartilha 96 por cento de similaridade com o genoma do SARS-CoV-2. O novo estudo comparou as proteanas de pico de ambos os varus e identificou várias diferenças importantes.
O SARS-CoV-2 e outros coronavarus usam suas proteanas de pico para ganhar entrada nas células ligando-se aos seus receptores desuperfÍcie, por exemplo, ACE2. Como uma fechadura e uma chave, a proteana do pico deve ter o formato certo para se ajustar aos receptores da canãlula, mas os receptores de cada animal tem uma forma ligeiramente diferente, o que significa que a proteana do pico se liga a alguns melhor do que a outros.Â
Para examinar se essas diferenças entre SARS-CoV-2 e RaTG13 estavam envolvidas na adaptação do SARS-CoV-2 aos humanos, os cientistas trocaram essas regiaµes e examinaram o quanto bem essas proteanas de pico resultantes se ligavam aos receptores ACE2 humanos - usando um manãtodo que não envolvem o uso de varus vivos.
Os resultados, publicados na revista PLOS Biology , mostraram que os picos de SARS-CoV-2 contendo regiaµes RaTG13 foram incapazes de se ligar aos receptores ACE2 humanos de forma eficaz, enquanto os picos de RaTG13 contendo regiaµes de SARS-CoV-2 poderiam se ligar de forma mais eficiente aos receptores humanos - embora não ao mesmonívelque a proteana de pico SARS-CoV-2 não editada. Isso potencialmente indica quemudanças semelhantes na proteana spike SARS-CoV-2 ocorreram historicamente, o que pode ter desempenhado um papel fundamental em permitir que o varus pule a barreira das espanãcies.
Os pesquisadores também investigaram se a proteana spike SARS-CoV-2 poderia se ligar aos receptores ACE2 de 22 animais diferentes para determinar qual deles, se houver, pode ser suscetavel a infecção. Eles demonstraram que os receptores de morcegos e pa¡ssaros fizeram as interações mais fracas com o SARS-CoV-2. A falta de ligação aos receptores do morcego acrescenta peso a evidência de que o SARS-CoV-2 provavelmente adaptou sua proteana spike quando saltou dos morcegos para as pessoas, possivelmente atravanãs de um hospedeiro intermediário.
Os receptores ACE2 de ca£es, gatos e bovinos foram identificados como os mais fortes interagentes com a proteana de pico SARS-CoV-2. A entrada eficiente nas células pode significar que a infecção pode ser mais facilmente estabelecida nesses animais, embora a ligação ao receptor seja apenas o primeiro passo na transmissão viral entre diferentes espanãcies animais.Â
“Como vimos com os surtos em fazendas de visons dinamarqueses no ano passado, éessencial entender quais animais podem ser infectados pelo SARS-CoV-2 e como as mutações na proteana do pico viral mudam sua capacidade de infectar diferentes espanãciesâ€, disse Graham.
A suscetibilidade de um animal a infecção e sua capacidade subsequente de infectar outras pessoas depende de uma sanãrie de fatores - incluindo se o SARS-CoV-2 écapaz de se replicar uma vez dentro das células e a capacidade do animal de lutar contra o varus. Mais estudos são necessa¡rios para entender se o gado e os animais de companhia podem ser receptivos a infecção por COVID-19 em humanos e atuar como reservata³rios para essa doena§a.
Esta pesquisa foi financiada pelo Conselho de Pesquisa Manãdica, Conselho de Pesquisa em Biotecnologia e Ciências Biola³gicas e Innovate UK - todos parte do UK Research and Innovation; a Royal Society e Wellcome.