Os novos biossensores permitem o registro e imagem simulta¢neos de tecidos e órgãos durante procedimentos ciraºrgicos.
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)
Os novos biossensores permitem o registro e imagem simulta¢neos de tecidos e órgãos durante procedimentos ciraºrgicos. Nesta foto, os pesquisadores anexaram o biossensor ao coração de um porco que foi obtido comercialmente. Crédito: Bongjoong Kim, Purdue University.
Uma equipe de pesquisa do Laborata³rio Nacional de Los Alamos e da Universidade de Purdue desenvolveu bio-tintas para biossensores que podem ajudar a localizar regiaµes craticas em tecidos e órgãos durante operações cirúrgicas.
"A tinta usada nos biossensores ébiocompatavel e oferece um design amiga¡vel com excelentes prazos de trabalho de mais de um dia", disse Kwan-Soo Lee, do grupo de Diagnóstico Quamico e Engenharia de Los Alamos.
Os novos biossensores permitem o registro e imagem simulta¢neos de tecidos e órgãos durante procedimentos ciraºrgicos.
"O registro e a imagem simulta¢neos podem ser aºteis durante a cirurgia cardaaca para localizar regiaµes craticas e orientar as intervenções cirúrgicas, como um procedimento para restaurar os ritmos cardaacos normais", disse Chi Hwan Lee, professor assistente de engenharia biomédica e professor assistente de meca¢nica da Leslie A. Geddes Engenharia e, por cortesia, de Engenharia de Materiais na Purdue University.
Los Alamos foi responsável por formular e sintetizar as biotintas, com o objetivo de criar um material ultramacio, fino e ela¡stico para biossensores que seja capaz de interagir perfeitamente com asuperfÍcie dos órgãos. Eles fizeram isso usando técnicas de impressão 3D.
"Os materiais de silicone são laquidos e fluem como o mel, por isso émuito difacil imprimir em 3D sem problemas de flacidez e flacidez durante a impressão", disse Kwan-Soo Lee. "a‰ muito emocionante ter encontrado uma maneira de criar tintas impressas que não tenham nenhuma deformação de forma durante o processo de cura."
As biotintas são mais macias do que o tecido, esticam sem sofrer degradação do sensor e tem adesão natural confia¡vel a superfÍcie aºmida dos órgãos sem a necessidade de adesivos adicionais.
Craig Goergen, o Professor Associado Leslie A. Geddes de Engenharia Biomédica na Purdue University, auxiliou na avaliação in vivo do adesivo atravanãs de testes em ratos e porcos. Os resultados mostraram que o biossensor foi capaz de medir o sinal elanãtrico de forma confia¡vel , sem prejudicar a função cardaaca.
A pesquisa foi publicada hoje na Nature Communications .